Language: 日本語English

boltz-api-cli Codex Plugin

Author
Boltz
Category
Education & Research
Topics
AI Agents & AI App Development · Web Search, Research & Learning
Version
0.1.1
First seen
2026-07-12
Last confirmed
2026-07-13
Explanation last updated
2026-07-12

The explanation below is AI-generated. Please verify it against the sources.

Boltz-api-cli is a Codex plugin, developed by Boltz, that connects Codex to the Boltz API for biomolecular modeling. According to the plugin manifest, it lets users predict structure and binding for protein, RNA, DNA, and ligand complexes, rank small-molecule or protein libraries against targets, and design small molecules, peptides, antibodies, nanobodies, or custom protein binders with structures and confidence metrics. The plugin has Interactive and Write capabilities and is categorized under Education & Research. The Boltz homepage describes Boltz as a research lab building generative AI models for biology and chemistry, offering the Boltz API alongside open-source models such as Boltz-2 and BoltzGen. Pricing details are not stated in the provided sources.

Overview

According to the boltz.bio homepage, Boltz is a research lab that builds frontier AI models for biomolecular design and offers the Boltz API as a product for integrating biomolecular models into agentic pipelines, with Python and TypeScript client support, deployment options (multi-tenant, single-tenant, on-premise), SOC 2 Type 1 verification, and role-based access control. The boltz-api-cli plugin exposes this API inside Codex.

What you can do with boltz-api-cli

  • Predict structure and binding for protein, RNA, DNA, and ligand complexes (per plugin.json longDescription)
  • Rank (screen) small-molecule or protein libraries against a target
  • Design novel small molecules, peptides, antibodies, nanobodies, or custom protein binders with structures and confidence metrics
  • Example prompts given in the manifest: "Predict EGFR L858R binding to osimertinib", "Design nanobodies for a SARS-CoV-2 RBD epitope", "Design selective JAK2 binders from Enamine REAL"
  • Access the underlying Boltz API via Python or TypeScript client code, per the boltz.bio homepage

Sources

Original description (English)

Predict structures, screen molecules and proteins, and design binders.

History of boltz-api-cli

Back to list